Melanosis Coli due to Rhubarb Supplementation

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Melanosis coli.

n engl j med 368;24 nejm.org june 13, 2013 2303 A 50-year-old woman underwent colonoscopy for rectal bleeding. Her entire colon appeared dark brown and black, a finding consistent with the diagnosis of melanosis coli (Panel A). Random biopsy specimens from the descending colon revealed sheets and clusters of macrophages laden with brownish pigment in the lamina propria (Panel B, arrow). A tiny,...

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Melanosis coli

Melanosis coli denotes brownish discoloration of the colonic mucosa found on endoscopy or histopathologic examination. The condition has no specific symptom on its own. It is a fairly frequent incidental finding of colonic biopsies and resection specimens. The pigmentation is caused by apoptotic cells which are ingested by macrophages and subsequently transported into the lamina propria, where ...

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Melanosis coli in patients with colon cancer

INTRODUCTION Melanosis coli is a benign lesion affecting the mucosa of the large intestine. There is a relationship between the presence of melanosis and anthraquinone laxative use. Melanosis coli is also observed in patients with colon cancer, but there is doubt whether these two conditions are related. AIM To analyze the correlation between melanosis and colon cancer. MATERIAL AND METHODS...

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Melanosis coli: a rarity in digestive endoscopy

A 61-year-old patient underwent endoscopic exploration for anemic syndrome. His medical history revealed that he had been taking a drug based on a mixture of medicinal herbs as laxative for nine years. This product consists of anthranoid-containing laxatives as aloe, senna, rhubarb, cascara and frangula. Endoscopy revealed diffuse dark brown pigmentation throughout his colon, which is compatibl...

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Melanosis Coli After Long-Term Ingestion of Cape Aloe

A73-year-oldwhitemalepresented toa tertiary center after an initial colonoscopy at an outside hospital showed at least 15 polyps, the largestmeasuring2.3 cm. Thepatientdeniedany family history of colorectal neoplasia and has undergone several colonoscopies since that time with mucosal resection of numerous polyps throughout the colon. The largest polyp was a 2.3-cm tubular adenoma in the cecum....

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ژورنال

عنوان ژورنال: ACG Case Reports Journal

سال: 2019

ISSN: 2326-3253

DOI: 10.14309/crj.0000000000000092